Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.74 |
| ▸ | ESR1 | P03372 | 4/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.74 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | AR | P10275 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Allylestrenol SCHEMBL10406336 | 0.85 | ESR1 (1.00) | PGRESR1SLC6A4CHRM2SLC6A2 | |
| Allylestrenol SCHEMBL19645390 | 0.85 | ESR1 (1.00) | PGRESR1SLC6A4CHRM2SLC6A2 | |
| Allylestrenol SCHEMBL29648200 | 0.85 | ESR1 (1.00) | PGRESR1SLC6A4CHRM2SLC6A2 | |
| Allylestrenol SCHEMBL329623 | 0.85 | ESR1 (1.00) | PGRESR1SLC6A4CHRM2SLC6A2 | |
| SCHEMBL21807745 | 0.77 | CYP2C19 (0.74) | PGRESR1SLC6A4CHRM2SLC6A2 | |
| SCHEMBL27048593 | 0.76 | PGR (0.61) | PGRESR1SLC6A4CHRM2SLC6A2 | |
| Ethylestrenol SCHEMBL147908 | 0.75 | SLC6A4 (1.00) | PGRESR1SLC6A4CHRM2SLC6A2 | |
| Ethylestrenol SCHEMBL11217999 | 0.75 | SLC6A4 (1.00) | PGRESR1SLC6A4CHRM2SLC6A2 | |
| SCHEMBL11857916 | 0.74 | PGR (0.74) | PGRESR1SLC6A4CHRM2SLC6A2 | |
| SCHEMBL11794232 | 0.74 | PDK1 (0.68) | PGRESR1SLC6A4CHRM2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127447-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH | 2018-05-10 | — | — | US | disclosed |
| US-9850268-B2 | Metathesis catalysts and methods thereof | TRUSTEES OF BOSTON COLLEGE (US) | 2017-12-26 | — | — | US | disclosed |
| US-20160194343-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194343-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | INF2, AFF2, KRAS | PGR 3313/4885ESR1 672/4885SLC6A4 3535/4885 |
| US-20180127447-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | INF2, AFF2, KRAS | PGR 3313/4885ESR1 672/4885SLC6A4 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.