Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17891660 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL17891664 | 0.84 | ALDH1A1 (0.56) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL1401247 | 0.83 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL14204903 | 0.80 | ALDH1A1 (0.61) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL27174611 | 0.79 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL3380568 | 0.79 | ALDH1A1 (0.63) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL291132 | 0.79 | ALDH1A1 (0.63) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL30954762 | 0.79 | ALDH1A1 (0.63) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL8070812 | 0.78 | ALDH1A1 (0.75) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL15987982 | 0.77 | ALDH1A1 (0.65) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127447-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH | 2018-05-10 | — | — | US | disclosed |
| US-9850268-B2 | Metathesis catalysts and methods thereof | TRUSTEES OF BOSTON COLLEGE (US) | 2017-12-26 | — | — | US | disclosed |
| US-20160194343-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194343-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | INF2, AFF2, KRAS | ALDH1A1 296/4885LMNA 940/4885KDM4E 1316/4885 |
| US-20180127447-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | INF2, AFF2, KRAS | ALDH1A1 296/4885LMNA 940/4885KDM4E 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.