SCHEMBL291132

SCHEMBL291132

CC1CCC(C(C)C)C(OCCCCO)C1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.63
LMNA P02545 2/20 0.49
KDM4E B2RXH2 1/20 0.47
APOBEC3A P31941 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47
GAA P10253 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
TRPA1 O75762 2/20 0.44
TRPM8 Q7Z2W7 2/20 0.44
P2RX4 Q99571 1/20 0.43
EPHX1 P07099 3/20 0.43
NTSR1 P30989 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HPGD P15428 1/20 0.42
CYP19A1 P11511 2/20 0.41
MAPT P10636 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3380568 1.00 ALDH1A1 (0.63) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL30954762 1.00 ALDH1A1 (0.63) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL14204903 0.98 ALDH1A1 (0.61) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL116765 0.95 ALDH1A1 (0.65) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL4582819 0.95 ALDH1A1 (0.65) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL943408 0.95 ALDH1A1 (0.65) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL15987982 0.95 ALDH1A1 (0.65) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL1617841 0.92 ALDH1A1 (0.58) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL1617541 0.91 ALDH1A1 (0.60) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL3388061 0.90 ALDH1A1 (0.67) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4471118-A1 PACKAGED CARBONATED ALCOHOLIC BEVERAGE CONTAINING GIN AND PRODUCTION METHOD THEREFOR Suntory Holdings Limited (JP) 2024-12-04 EP claimed
EP-3494104-B1 WARMING SENSATION COMPOUNDS TAKASAGO PERFUMERY CO LTD (JP) 2023-11-15 EP claimed
WO-2023145633-A1 PACKAGED CARBONATED ALCOHOLIC BEVERAGE CONTAINING GIN AND PRODUCTION METHOD THEREFOR サントリーホールディングス株式会社 2023-08-03 WO claimed
CN-111032003-B Cooling and flavor enhancing compositions 弗门尼舍有限公司 2023-03-17 CN claimed
EP-3658109-B1 COOLING AND FLAVOR BOOSTING COMPOSITIONS FIRMENICH & CIE (CH) 2022-12-07 EP claimed
CN-109803948-B Warming sensation compound 高砂香料工业株式会社 2022-03-01 CN claimed
US-11059771-B2 Warming sensation compounds TAKASAGO INTERNATIONAL CORPORATION (JP) 2021-07-13 US claimed
US-11034644-B2 2021-06-15 US claimed
EP-3658109-A1 COOLING AND FLAVOR BOOSTING COMPOSITIONS Firmenich SA (CH) 2020-06-03 EP claimed
CN-111032003-A Cooling and flavor enhancing compositions 弗门尼舍有限公司 2020-04-17 CN claimed
EP-1885275-A1 TOPICAL WARMING COMPOSITION Takasago International Corporation (USA) (US) 2008-02-13 EP claimed
EP-1761238-A1 MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION COMPRISING THE SAME Takasago International Corporation (JP) 2007-03-14 EP claimed
WO-2007022056-A2 SENSATION MASKING COMPOSITION TAKASAGO INTERNATIONAL CORP. (USA) (US) 2007-02-22 WO claimed
WO-2007004740-A1 VANILLIN ACETALS AND SENSORY STIMULANT COMPOSITION CONTAINING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-01-11 WO claimed
WO-2006137556-A1 FLAVOR AND FRAGRANCE COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-12-28 WO claimed
WO-2006130710-A1 TOPICAL WARMING COMPOSITION TAKASAGO INTERNATIONAL CORP. (USA) (US) 2006-12-07 WO claimed
EP-1689256-A1 FOOD PRODUCTS CONTAINING A FRUIT COMPONENT Takasago International Corporation (JP) 2006-08-16 EP claimed
WO-2005115325-A1 MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION COMPRISING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-12-08 WO claimed
WO-2005048743-A1 FOOD PRODUCTS CONTAINING A FRUIT COMPONENT TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-06-02 WO claimed
US-6899901-B2 Sensate composition imparting initial sensation upon contact TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-05-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11059771-B2 Warming sensation compounds TRPA1, TRPV1, TRPV4 ALDH1A1 1286/4885LMNA 4043/4885KDM4E 4002/4885
US-11034644-B2 TRPA1, TRPV1, TRPV5 ALDH1A1 593/4885LMNA 3952/4885KDM4E 3702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.