Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL30040945 | 0.92 | KMT2A (0.41) | ALDH1A1GAASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL273450 | 0.86 | CA12 (0.41) | ALDH1A1GAASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5332415 | 0.79 | GAA (0.46) | ALDH1A1GAASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL1603835 | 0.77 | GAA (0.41) | ALDH1A1GAASMN1; SMN2PKMCYP3A4 | |
| SCHEMBL2848424 | 0.75 | CA12 (0.40) | ALDH1A1GAALMNAL3MBTL1HTT | |
| SCHEMBL31438232 | 0.73 | STAT3 (0.38) | ALDH1A1GAASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL12611117 | 0.73 | STAT3 (0.38) | ALDH1A1GAASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL5212059 | 0.73 | GAA (0.48) | ALDH1A1GAASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL9341811 | 0.73 | GAA (0.48) | ALDH1A1GAASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL9770800 | 0.72 | GAA (0.46) | ALDH1A1GAASMN1; SMN2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084876-A | Construction method of indole 3 a-aryl hydroindolone carbon skeleton | 宁夏大学 | 2024-05-28 | — | — | CN | claimed |
| CN-116970015-A | Fluorinated monosaccharide derivative and synthetic method and application thereof | 中国科学院精密测量科学与技术创新研究院 | 2023-10-31 | — | — | CN | claimed |
| CN-118084876-A | Construction method of indole 3 a-aryl hydroindolone carbon skeleton | 宁夏大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084876-A | Construction method of indole 3 a-aryl hydroindolone carbon skeleton | 宁夏大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-116970015-A | Fluorinated monosaccharide derivative and synthetic method and application thereof | 中国科学院精密测量科学与技术创新研究院 | 2023-10-31 | — | — | CN | disclosed |
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |
| EP-4134104-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | Eubulus Biotherapeutics Inc. (CN) | 2023-02-15 | — | — | EP | disclosed |
| WO-2016107578-A1 | HALOGENATED S-(PERFLUOROALKYL) DIBENZOTHIOPHENIUM SALT AND ITS PRODUCTION METHODS | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | UCHL3, UBE2L3, ADAM33 | ALDH1A1 2539/4885GAA 520/4885SMN1; SMN2 2462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.