Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | RAD52 | P43351 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10307404 | 0.98 | HSP90AA1 (0.59) | HSP90AA1LMNANPSR1APAF1SMN1; SMN2 | |
| Bromide SCHEMBL17906580 | 0.97 | HSP90AA1 (0.62) | HSP90AA1LMNANPSR1APAF1SMN1; SMN2 | |
| Iodide SCHEMBL1787088 | 0.94 | HSP90AA1 (0.67) | HSP90AA1LMNANPSR1APAF1SMN1; SMN2 | |
| Iodide SCHEMBL1788625 | 0.94 | HSP90AA1 (0.67) | HSP90AA1LMNANPSR1APAF1SMN1; SMN2 | |
| SCHEMBL14387168 | 0.92 | HSP90AA1 (0.68) | HSP90AA1LMNANPSR1APAF1SMN1; SMN2 | |
| SCHEMBL31023557 | 0.92 | HSP90AA1 (0.68) | HSP90AA1LMNANPSR1APAF1SMN1; SMN2 | |
| Water SCHEMBL9000149 | 0.91 | HSP90AA1 (0.67) | HSP90AA1LMNANPSR1APAF1SMN1; SMN2 | |
| Iodide SCHEMBL5325008 | 0.90 | HSP90AA1 (0.50) | HSP90AA1LMNANPSR1APAF1SMN1; SMN2 | |
| SCHEMBL10307406 | 0.88 | HSP90AA1 (0.51) | HSP90AA1LMNANPSR1APAF1SMN1; SMN2 | |
| SCHEMBL14075499 | 0.86 | LMNA (0.56) | HSP90AA1LMNANPSR1APAF1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102082030-B | Colloidal electrolyte, preparation method thereof and dye-sensitized solar cell | IND TECH RES INST | 2012-10-31 | — | — | CN | disclosed |
| US-8287753-B2 | Gel electrolyte composition, method of fabricating thereof and dye-sensitized solar cell using the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-10-16 | — | — | US | disclosed |
| CN-102082030-A | Colloidal electrolyte, preparation method thereof and dye-sensitized solar cell | IND TECH RES INST | 2011-06-01 | — | — | CN | disclosed |
| US-20110114167-A1 | GEL ELECTROLYTE COMPOSITION, METHOD OF FABRICATING THEREOF AND DYE-SENSITIZED SOLAR CELL USING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2011-05-19 | — | — | US | disclosed |