Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1168392 | 0.84 | L3MBTL1 (0.45) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL17893795 | 0.83 | MEN1 (0.41) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL17899967 | 0.82 | MAPT (0.41) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL17893687 | 0.81 | NR1H4 (0.35) | SMN1; SMN2MEN1KMT2ANR1H4NFKB1 | |
| SCHEMBL26728954 | 0.81 | L3MBTL1 (0.42) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL26728812 | 0.81 | L3MBTL1 (0.42) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL20127207 | 0.81 | MEN1 (0.56) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL21394268 | 0.80 | MEN1 (0.55) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL21394247 | 0.80 | MEN1 (0.55) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL21394333 | 0.80 | MEN1 (0.55) | SMN1; SMN2MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180002597-A1 | Fluorene Derivatives as Light Emitting Elements for Electroluminescent Devices | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2018-01-04 | — | — | US | disclosed |
| EP-3240856-A1 | FLUORENE DERIVATIVES AS LIGHT EMITTING ELEMENTS FOR ELECTROLUMINESCENT DEVICES | Dow Global Technologies LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016109274-A1 | FLUORENE DERIVATIVES AS LIGHT EMITTING ELEMENTS FOR ELECTROLUMINESCENT DEVICES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180002597-A1 | Fluorene Derivatives as Light Emitting Elements for Electroluminescent Devices | LEF1, AFF2, CELF2 | SMN1; SMN2 3267/4885MAPT 3724/4885MEN1 1722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.