Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 10/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30791008 | 0.98 | PI4KA (0.41) | PI4KAPI4K2BPI4K2API4KBIRAK4 | |
| SCHEMBL1369046 | 0.76 | PDE4A (0.43) | IRAK4DYRK1AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2971145 | 0.74 | IRAK4 (0.39) | IRAK4 | |
| SCHEMBL12559881 | 0.74 | IRAK4 (0.39) | IRAK4 | |
| SCHEMBL12143633 | 0.74 | IRAK4 (0.42) | IRAK4 | |
| SCHEMBL29118643 | 0.74 | IRAK4 (0.49) | IRAK4LIMK1MAP4K4DYRK1AKDM4E | |
| SCHEMBL13262134 | 0.71 | NCF1 (0.43) | IRAK4DYRK1AMEN1MAPTBLM | |
| SCHEMBL30504301 | 0.71 | NCF1 (0.43) | IRAK4DYRK1AMEN1MAPTBLM | |
| SCHEMBL3705558 | 0.70 | DCPS (0.47) | ALDH1A1HPGDHSD17B10ADORA2A | |
| SCHEMBL12559307 | 0.69 | IRAK4 (0.46) | IRAK4MEN1ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117487318-B | Fireproof bus duct based on epoxy resin and preparation method thereof | 江苏盈聚电气有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117487318-A | Fireproof bus duct based on epoxy resin and preparation method thereof | 江苏盈聚电气有限公司 | 2024-02-02 | — | — | CN | claimed |
| US-20080261823-A1 | Fluorescent Nucleoside Analogs That Mimic Naturally Occurring Nucleosides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-10-23 | — | — | US | claimed |
| CN-118660872-A | Pyrimidine compound, preparation method and medical application thereof | 江苏亚虹医药科技股份有限公司 | 2024-09-17 | — | — | CN | disclosed |
| EP-4346806-A2 | IMIDAZOLE-CONTAINING INHIBITORS OF ALK2 KINASE | Biocryst Pharmaceuticals, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| CN-117487318-B | Fireproof bus duct based on epoxy resin and preparation method thereof | 江苏盈聚电气有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117487318-B | Fireproof bus duct based on epoxy resin and preparation method thereof | 江苏盈聚电气有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117487318-A | Fireproof bus duct based on epoxy resin and preparation method thereof | 江苏盈聚电气有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117487318-A | Fireproof bus duct based on epoxy resin and preparation method thereof | 江苏盈聚电气有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116496252-A | Pyrimidine compound, preparation method and medical application thereof | 江苏亚虹医药科技股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| WO-2022251188-A2 | IMIDAZOLE-CONTAINING INHIBITORS OF ALK2 KINASE | BIOCRYST PHARMACEUTICALS, INC. (US) | 2022-12-01 | — | — | WO | disclosed |
| WO-2007079861-A1 | NOVEL, CYCLIC SUBSTITUTED FUROPYRIMIDINE DERIVATIVES AND USE THEREOF FOR TREATING CARDIOVASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007038387-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRUSES AND CANCER | YALE UNIVERSITY (US) | 2007-04-05 | — | — | WO | disclosed |
| EP-1768986-A2 | FURANOPYRIMIDINES | Amgen Inc. (US) | 2007-04-04 | — | — | EP | disclosed |
| US-20060040961-A1 | Furanopyrimidines | AMGEN INC. | 2006-02-23 | — | — | US | disclosed |
| WO-2006004658-A2 | FURANOPYRIMIDINES | AMGEN INC. (US) | 2006-01-12 | — | — | WO | disclosed |
| WO-2005092896-A1 | COMPOUND FOR INHIBITING TYROSINE KINASE ACTIVITY OF DDR2 PROTEIN | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-10-06 | — | — | WO | disclosed |
| US-20040259888-A1 | Novel 4-aminofuropyrimidines and the use thereof | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-12-23 | — | — | US | disclosed |
| EP-1425283-A1 | NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF | Bayer HealthCare AG (DE) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003018589-A1 | NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040961-A1 | Furanopyrimidines | TYMS, IDO1, NFATC1 | PI4KA 1824/4885PI4K2B 3629/4885PI4K2A 3730/4885 |
| US-20080261823-A1 | Fluorescent Nucleoside Analogs That Mimic Naturally Occurring Nucleosides | NSUN2, NSUN3, NCL | PI4KA 3966/4885PI4K2B 4310/4885PI4K2A 4097/4885 |
| US-20040259888-A1 | Novel 4-aminofuropyrimidines and the use thereof | DPYD, TPMT, TYMP | PI4KA 2367/4885PI4K2B 2159/4885PI4K2A 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.