SCHEMBL17895680

SCHEMBL17895680

CCCC(O)(c1nc2cccc(Br)c2s1)c1cnccc1C(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17895580 0.85 ALOX5 (0.33) ALOX5
SCHEMBL17895619 0.84 CASR (0.36) ALOX5
SCHEMBL17895621 0.83 RORC (0.30) ALOX5
SCHEMBL17895649 0.82 ALOX5 (0.33) ALOX5
SCHEMBL17895722 0.80 KCNA5 (0.38) ALOX5
SCHEMBL17895719 0.80 PPARA (0.36) —
SCHEMBL17895704 0.77 PDE5A (0.34) ALOX5
SCHEMBL17895573 0.75 CA12 (0.33) ALOX5
SCHEMBL17895697 0.74 CASR (0.36) ALOX5
SCHEMBL17895585 0.73 RXFP1 (0.33) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107531631-B Methods and agents for treating diseases 安吉昂生物医药公司 2021-09-03 — — CN claimed
CN-107531631-B Methods and agents for treating diseases 安吉昂生物医药公司 2021-09-03 — — CN disclosed
EP-3240778-A1 METHODS AND AGENTS FOR TREATING DISEASE Angion Biomedica Corp. (US) 2017-11-08 — — EP disclosed
WO-2016109492-A1 METHODS AND AGENTS FOR TREATING DISEASE ANGION BIOMEDICA CORP (US) 2016-07-07 — — WO disclosed
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