Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.47 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29690511 | 0.91 | ALOX15 (0.51) | HTTALOX15SMN1; SMN2LMNAHPGD | |
| SCHEMBL25062714 | 0.85 | SMN1; SMN2 (0.61) | HTTALOX15SMN1; SMN2LMNAHTR1A | |
| SCHEMBL26785759 | 0.82 | ALOX15 (0.57) | HTTALOX15SMN1; SMN2LMNAHTR1A | |
| SCHEMBL29690521 | 0.82 | UBE2T (0.53) | HTTALOX15SMN1; SMN2HPGDRAB9A | |
| SCHEMBL2034241 | 0.80 | SMN1; SMN2 (0.62) | HTTALOX15SMN1; SMN2LMNAHTR1A | |
| SCHEMBL28822363 | 0.79 | ALOX15 (0.55) | HTTALOX15SMN1; SMN2LMNAHTR1A | |
| SCHEMBL9641726 | 0.79 | SMN1; SMN2 (0.70) | HTTALOX15SMN1; SMN2LMNAHTR1A | |
| SCHEMBL175532 | 0.79 | ALOX15 (0.60) | HTTALOX15SMN1; SMN2LMNAHTR1A | |
| Benzene SCHEMBL28273759 | 0.79 | SMN1; SMN2 (0.65) | HTTALOX15SMN1; SMN2LMNAHTR1A | |
| SCHEMBL31173766 | 0.79 | ALOX15 (0.60) | HTTALOX15SMN1; SMN2LMNAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240778-A1 | METHODS AND AGENTS FOR TREATING DISEASE | Angion Biomedica Corp. (US) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016109492-A1 | METHODS AND AGENTS FOR TREATING DISEASE | ANGION BIOMEDICA CORP (US) | 2016-07-07 | — | — | WO | disclosed |