Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.50 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26785759 | 0.88 | ALOX15 (0.57) | ALOX15HTTSMN1; SMN2HTR1ADRD2 | |
| SCHEMBL9641726 | 0.82 | SMN1; SMN2 (0.70) | ALOX15HTTSMN1; SMN2HTR1ADRD2 | |
| SCHEMBL25062714 | 0.81 | SMN1; SMN2 (0.61) | ALOX15HTTSMN1; SMN2HTR1ADRD2 | |
| SCHEMBL14131194 | 0.81 | UBE2T (0.56) | ALOX15HTTSMN1; SMN2HTR1ADRD2 | |
| SCHEMBL27509034 | 0.80 | SMN1; SMN2 (0.68) | ALOX15HTTSMN1; SMN2HTR1ADRD2 | |
| SCHEMBL17895733 | 0.79 | HTT (0.56) | ALOX15HTTSMN1; SMN2HTR1ADRD2 | |
| SCHEMBL20358330 | 0.79 | SMN1; SMN2 (0.62) | ALOX15HTTSMN1; SMN2HTR1ADRD2 | |
| SCHEMBL2034241 | 0.79 | SMN1; SMN2 (0.62) | ALOX15HTTSMN1; SMN2HTR1ADRD2 | |
| Bromide SCHEMBL11522514 | 0.79 | SMN1; SMN2 (0.66) | ALOX15HTTSMN1; SMN2HTR1ADRD2 | |
| SCHEMBL27924411 | 0.78 | SMN1; SMN2 (0.51) | ALOX15HTTSMN1; SMN2HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910098-B | Synthesis method of 2-arylbenzothiazole compound | 大连理工大学 | 2017-03-22 | — | — | CN | disclosed |
| CN-104910098-A | Synthesis method of 2-arylbenzothiazole compound | UNIV DALIAN TECH | 2015-09-16 | — | — | CN | disclosed |