Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17895957 | 0.82 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL17895809 | 0.81 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL17895744 | 0.77 | AGTR1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL17895866 | 0.77 | AGTR1 (0.33) | AGTR1AGTR2 | |
| SCHEMBL17895797 | 0.76 | AGTR1 (0.34) | AGTR1AGTR2 | |
| SCHEMBL17895928 | 0.76 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL17895840 | 0.76 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL17895860 | 0.70 | CYP1A2 (0.40) | AGTR1AGTR2 | |
| SCHEMBL17895748 | 0.68 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL17895762 | 0.67 | AGTR1 (0.46) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |