Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17895809 | 0.83 | AGTR1 (0.37) | AGTR1AGTR2ALDH1A1KDM4EHPGD | |
| SCHEMBL17895928 | 0.80 | AGTR1 (0.40) | AGTR1AGTR2ALDH1A1KDM4EHPGD | |
| SCHEMBL17895797 | 0.78 | AGTR1 (0.34) | AGTR1AGTR2ALDH1A1KDM4EHPGD | |
| SCHEMBL17895840 | 0.77 | AGTR1 (0.40) | AGTR1AGTR2ALDH1A1KDM4EHPGD | |
| SCHEMBL17895770 | 0.77 | AGTR1 (0.34) | AGTR1AGTR2 | |
| SCHEMBL17895866 | 0.76 | AGTR1 (0.33) | AGTR1AGTR2 | |
| SCHEMBL17896034 | 0.73 | LMNA (0.35) | ALDH1A1KDM4ELMNA | |
| SCHEMBL17895860 | 0.72 | CYP1A2 (0.40) | AGTR1AGTR2ALDH1A1KDM4EHPGD | |
| SCHEMBL17895957 | 0.72 | AGTR1 (0.39) | AGTR1AGTR2ALDH1A1KDM4EHPGD | |
| SCHEMBL17895748 | 0.70 | AGTR1 (0.45) | AGTR1AGTR2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |