Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20337690 | 0.86 | CYP11B2 (0.77) | CYP11B2CYP11B1 | |
| SCHEMBL458680 | 0.85 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL17896618 | 0.82 | CYP11B2 (0.71) | CYP11B2CYP11B1 | |
| SCHEMBL17896605 | 0.82 | CYP11B2 (0.71) | CYP11B2CYP11B1 | |
| SCHEMBL17897055 | 0.82 | CYP11B2 (0.88) | CYP11B2CYP11B1 | |
| SCHEMBL17896606 | 0.81 | CYP11B2 (0.66) | CYP11B2CYP11B1 | |
| SCHEMBL17896608 | 0.81 | CYP11B2 (0.66) | CYP11B2CYP11B1 | |
| SCHEMBL17896656 | 0.80 | CYP11B2 (0.53) | CYP11B2CYP11B1 | |
| SCHEMBL20338196 | 0.80 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL461228 | 0.79 | CYP11B2 (0.71) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382226-B2 | Aldosterone synthase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-07-05 | — | — | US | disclosed |
| US-9382226-B2 | Aldosterone synthase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-07-05 | — | — | US | disclosed |