Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360322 | 0.89 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL6420071 | 0.86 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL2792782 | 0.80 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL18259873 | 0.79 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL28389705 | 0.77 | RAB9A (0.65) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL9879624 | 0.77 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL9879622 | 0.77 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL16142366 | 0.77 | CA1 (0.61) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL23600 | 0.76 | CA1 (0.80) | NPC1RAB9ACA1CA2TDP1 | |
| SCHEMBL13267179 | 0.76 | ALDH1A1 (0.55) | NPC1RAB9ASMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059185-A1 | PROCESS FOR PRODUCING POLYETHER-POLYESTER BLOCK COPOLYMER | RHODIA (CHINA) CO., LTD. (CN) | 2012-03-08 | — | — | US | disclosed |
| WO-2011000158-A1 | PROCESS FOR PRODUCING POLYETHER-POLYESTER BLOCK COPOLYMER | RHODIA (CHINA) CO., LTD. (CN) | 2011-01-06 | — | — | WO | disclosed |