Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.73 |
| ▸ | AKT1 | P31749 | 1/20 | 0.73 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMO | Q99835 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17897757 | 0.90 | AKT1 (0.60) | PDPK1AKT1EPHX1ALDH1A1MAPT | |
| SCHEMBL15777246 | 0.85 | PDPK1 (0.53) | PDPK1AKT1EPHX1ALDH1A1MAPT | |
| SCHEMBL350752 | 0.85 | AKT1 (1.00) | PDPK1AKT1EPHX1ALDH1A1MAPT | |
| SCHEMBL16119683 | 0.82 | EPHX1 (0.81) | EPHX1ALDH1A1MAPTSMN1; SMN2ALOX12 | |
| SCHEMBL15788804 | 0.80 | AKT1 (0.73) | PDPK1AKT1EPHX1ALDH1A1MAPT | |
| SCHEMBL3047473 | 0.78 | KMT2A (0.54) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL15778848 | 0.77 | PDPK1 (0.73) | PDPK1AKT1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11161985 | 0.76 | EPHX1 (0.70) | EPHX1ALDH1A1MAPTGAALMNA | |
| SCHEMBL3050807 | 0.76 | KMT2A (0.55) | ALDH1A1MAPTGAALMNAMEN1 | |
| SCHEMBL17897764 | 0.76 | AKT1 (0.67) | AKT1EPHX1ALDH1A1MAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160194279-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194279-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | TRRAP, NAT1, AHR | PDPK1 4430/4885AKT1 2603/4885EPHX1 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.