SCHEMBL1789794

SCHEMBL1789794

CC(F)(F)OC(=O)Oc1cc(C(C)(C)C)cc(C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.39
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
RXRB P28702 5/20 0.35
RXRA P19793 4/20 0.35
RXRG P48443 3/20 0.35
ACHE P22303 1/20 0.34
MAPT P10636 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
RAB9A P51151 4/20 0.33
TRPV1 Q8NER1 1/20 0.32
CD69 Q07108 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
PRSS1 P07477 1/20 0.31
ACR P10323 1/20 0.31
NPC1 O15118 3/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1790890 0.85 ELANE (0.53) ELANEGABRA1GABRB2RXRBRXRA
SCHEMBL1790875 0.83 ACHE (0.47) ELANERXRBRXRAACHETRPV1
SCHEMBL1792266 0.82 MAPT (0.51) ELANEMAPTL3MBTL1TDP1RAB9A
SCHEMBL1791598 0.79 ELANE (0.37) ELANEGABRA1GABRB2RXRBRXRA
SCHEMBL1788545 0.78 ELANE (0.46) ELANEGABRA1GABRB2MAPTL3MBTL1
SCHEMBL1793096 0.77 ELANE (0.35) ELANEGABRA1GABRB2RXRBRXRA
SCHEMBL1787637 0.76 GABRA1 (0.35) ELANEGABRA1GABRB2RXRBRXRA
SCHEMBL1790638 0.76 ELANE (0.47) ELANEMAPTL3MBTL1TDP1RAB9A
SCHEMBL14488840 0.75 CYP3A4 (0.47) ELANEGABRA1GABRB2RXRBRXRA
SCHEMBL28088401 0.74 ELANE (0.49) ELANEMAPTL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2249426-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY MITSUBISHI CHEM CORP (JP) 2019-07-10 EP disclosed
US-9083058-B2 Nonaqueous electrolytic solution and nonaqueous-electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2015-07-14 US disclosed
US-8916298-B2 Nonaqueous electrolytic solution and nonaqueous-electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2014-12-23 US disclosed
US-8889302-B2 Nonaqueous electrolytic solution and nonaqueous-electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2014-11-18 US disclosed
US-8846254-B2 2014-09-30 US disclosed
US-20140134481-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2014-05-15 US disclosed
US-20120308883-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-12-06 US disclosed
US-20120219854-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
US-20110123871-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMCIAL (JP) 2011-05-26 US disclosed
EP-2249426-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY Mitsubishi Chemical Corporation (JP) 2010-11-10 EP disclosed