SCHEMBL17898229

SCHEMBL17898229

CC1Cc2ccccc2N1C(=O)CC1CCN(C/C=N/c2ccccc2N)CC1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 16/20 0.59
DRD2 P14416 14/20 0.59
ALDH1A1 P00352 4/20 0.51
CYP2D6 P10635 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13448941 0.89 ALDH1A1 (0.61) DRD4DRD2ALDH1A1CYP2D6
SCHEMBL13448942 0.77 DRD2 (0.54) DRD4DRD2ALDH1A1CYP2D6
SCHEMBL7659719 0.74 DRD4 (1.00) DRD4DRD2
SCHEMBL21250732 0.69 DRD4 (0.63) DRD4DRD2ALDH1A1
SCHEMBL18711265 0.67 NOTUM (0.69) DRD4DRD2ALDH1A1CYP2D6
SCHEMBL15746090 0.66 NOTUM (0.67) DRD4DRD2ALDH1A1CYP2D6
SCHEMBL11438312 0.66 NOTUM (0.67) DRD4DRD2ALDH1A1CYP2D6
SCHEMBL4220630 0.65 ALDH1A1 (0.61) DRD4DRD2ALDH1A1CYP2D6
SCHEMBL10859231 0.64 NOTUM (0.69) ALDH1A1
SCHEMBL1865732 0.64 NOTUM (0.73) ALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160196412-A1 DESIGN OF MOLECULES RECURSION PHARMACEUTICALS, INC. 2016-07-07 US disclosed
US-20160196412-A1 DESIGN OF MOLECULES RECURSION PHARMACEUTICALS, INC. 2016-07-07 US disclosed