Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 10/20 | 0.61 |
| ▸ | DRD1 | P21728 | 5/20 | 0.61 |
| ▸ | DRD2 | P14416 | 8/20 | 0.59 |
| ▸ | HTR7 | P34969 | 3/20 | 0.59 |
| ▸ | DRD5 | P21918 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898233 | 0.94 | DRD3 (0.53) | DRD3DRD1DRD2HTR7DRD5 | |
| SCHEMBL13448990 | 0.93 | DRD3 (0.65) | DRD3DRD1DRD2HTR7DRD5 | |
| SCHEMBL17898231 | 0.88 | DRD3 (0.60) | DRD3DRD1DRD2HTR7DRD5 | |
| SCHEMBL13449000 | 0.87 | DRD3 (0.77) | DRD3DRD1DRD2HTR7DRD5 | |
| SCHEMBL13448967 | 0.85 | DRD3 (0.80) | DRD3DRD1DRD2HTR7DRD5 | |
| SCHEMBL13448975 | 0.84 | DRD3 (0.79) | DRD3DRD1DRD2HTR7DRD5 | |
| SCHEMBL21250682 | 0.82 | DRD3 (0.65) | DRD3DRD1DRD2HTR7DRD5 | |
| SCHEMBL13448986 | 0.82 | DRD2 (0.57) | DRD3DRD1DRD2HTR7DRD5 | |
| SCHEMBL2027865 | 0.81 | DRD3 (0.70) | DRD3DRD1DRD2HTR7DRD5 | |
| SCHEMBL10835486 | 0.78 | DRD3 (0.64) | DRD3DRD1DRD2HTR7DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160196412-A1 | DESIGN OF MOLECULES | RECURSION PHARMACEUTICALS, INC. | 2016-07-07 | — | — | US | disclosed |
| US-20160196412-A1 | DESIGN OF MOLECULES | RECURSION PHARMACEUTICALS, INC. | 2016-07-07 | — | — | US | disclosed |