Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 13/20 | 0.64 |
| ▸ | DRD2 | P14416 | 12/20 | 0.64 |
| ▸ | HTR7 | P34969 | 3/20 | 0.64 |
| ▸ | DRD5 | P21918 | 1/20 | 0.64 |
| ▸ | DRD1 | P21728 | 3/20 | 0.56 |
| ▸ | DRD4 | P21917 | 8/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10835779 | 0.99 | DRD3 (0.62) | DRD3DRD2HTR7DRD5DRD1 | |
| SCHEMBL10834807 | 0.98 | DRD3 (0.66) | DRD3DRD2HTR7DRD5DRD1 | |
| SCHEMBL10834441 | 0.95 | DRD3 (0.58) | DRD3DRD2HTR7DRD5DRD1 | |
| SCHEMBL10836111 | 0.91 | DRD3 (0.51) | DRD3DRD2HTR7DRD5DRD1 | |
| SCHEMBL10835999 | 0.91 | DRD3 (0.51) | DRD3DRD2HTR7DRD5DRD1 | |
| SCHEMBL10835535 | 0.89 | DRD3 (0.47) | DRD3DRD2HTR7DRD5DRD1 | |
| SCHEMBL10835498 | 0.87 | DRD3 (0.61) | DRD3DRD2HTR7DRD5DRD1 | |
| SCHEMBL10835778 | 0.86 | DRD2 (0.68) | DRD3DRD2HTR7MEN1ALDH1A1 | |
| SCHEMBL10835105 | 0.85 | DRD3 (0.59) | DRD3DRD2HTR7DRD5DRD1 | |
| SCHEMBL10835894 | 0.84 | DRD2 (0.45) | DRD3DRD2HTR7DRD5DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585773-A | DIURETIC, HYPOTENSIVE | BRISTOL-MYERS COMPANY (US) | 1986-04-29 | — | — | US | claimed |
| US-8252814-B2 | Agents and crystals for improving excretory potency of urinary bladder | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-08-28 | — | — | US | disclosed |
| US-8252814-B2 | Agents and crystals for improving excretory potency of urinary bladder | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-08-28 | — | — | US | disclosed |
| US-20090264467-A1 | Agents and crystals for improving excretory potency of urinary bladder | ISHIHARA YUJI | 2009-10-22 | — | — | US | disclosed |
| US-20090264467-A1 | Agents and crystals for improving excretory potency of urinary bladder | ISHIHARA YUJI | 2009-10-22 | — | — | US | disclosed |
| US-4585773-A | DIURETIC, HYPOTENSIVE | BRISTOL-MYERS COMPANY (US) | 1986-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264467-A1 | Agents and crystals for improving excretory potency of urinary bladder | ACHE, BCHE, PDE7A | DRD3 2768/4885DRD2 2584/4885HTR7 1962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.