Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898353 | 0.95 | HRH3 (0.36) | HPGDHRH3GPR119 | |
| SCHEMBL17897394 | 0.91 | HPGD (0.40) | HPGDPTGESHRH3NFE2L2GPR119 | |
| SCHEMBL17897396 | 0.91 | HTR2A (0.37) | HPGDHRH3HTR1B | |
| SCHEMBL17898351 | 0.90 | HRH3 (0.34) | HPGDHRH3 | |
| SCHEMBL17898349 | 0.86 | HRH3 (0.34) | HPGDHRH3ALOX5APFEN1 | |
| SCHEMBL17084292 | 0.86 | RARB (0.38) | S1PR1S1PR3S1PR5HTR1B | |
| SCHEMBL17084295 | 0.86 | RARB (0.38) | S1PR1S1PR3S1PR5HTR1B | |
| SCHEMBL17084299 | 0.86 | RARB (0.38) | S1PR1S1PR3S1PR5HTR1B | |
| SCHEMBL17086819 | 0.86 | HTR2A (0.41) | HPGDHRH3S1PR1S1PR3S1PR5 | |
| SCHEMBL17086824 | 0.86 | HTR2A (0.41) | HPGDHRH3S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160194561-A1 | DIFLUOROPHENYL LIQUID CRYSTAL COMPOSITION | DIC CORPORATION (JP) | 2016-07-07 | — | — | US | disclosed |