Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898671 | 0.96 | — | — | |
| SCHEMBL15373970 | 0.94 | — | — | |
| SCHEMBL17899007 | 0.94 | RIPK1 (0.32) | RIPK1 | |
| SCHEMBL19628481 | 0.93 | RIPK1 (0.32) | RIPK1 | |
| SCHEMBL17898878 | 0.92 | RIPK1 (0.30) | RIPK1 | |
| SCHEMBL17898664 | 0.92 | CNR2 (0.33) | — | |
| SCHEMBL15860894 | 0.92 | CNR2 (0.31) | — | |
| SCHEMBL17899003 | 0.91 | — | — | |
| SCHEMBL15373969 | 0.90 | — | — | |
| SCHEMBL17899026 | 0.89 | HPGDS (0.31) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |