Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | REN | P00797 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898872 | 0.89 | NAAA (0.36) | NAAAGAABACE1 | |
| SCHEMBL17898650 | 0.87 | NAAA (0.39) | NAAAGAAREN | |
| SCHEMBL17898802 | 0.85 | BACE1 (0.40) | NAAABACE1 | |
| SCHEMBL15363832 | 0.84 | NAAA (0.39) | NAAAGAAREN | |
| SCHEMBL15363828 | 0.84 | NAAA (0.39) | NAAAGAAREN | |
| SCHEMBL17898717 | 0.84 | NAAA (0.39) | NAAAGAAREN | |
| SCHEMBL16605390 | 0.84 | NAAA (0.37) | NAAAGAAREN | |
| SCHEMBL17898651 | 0.83 | NAAA (0.40) | NAAAGAAREN | |
| SCHEMBL17898718 | 0.82 | NAAA (0.36) | NAAAGAAREN | |
| SCHEMBL19099668 | 0.82 | GAA (0.40) | NAAAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |