Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 5/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898650 | 0.87 | NAAA (0.39) | NAAAGAAF2F10PRSS1 | |
| SCHEMBL17898731 | 0.87 | GAA (0.39) | NAAAGAAF2F10PRSS1 | |
| SCHEMBL19628418 | 0.84 | NAAA (0.39) | NAAAGAAF2F10PRSS1 | |
| SCHEMBL17898784 | 0.84 | GAA (0.44) | NAAAGAAF2F10PRSS1 | |
| SCHEMBL17898717 | 0.84 | NAAA (0.39) | NAAAGAARENNFKB1NFKB2 | |
| SCHEMBL16605390 | 0.84 | NAAA (0.37) | NAAAGAAF2F10PRSS1 | |
| SCHEMBL17898720 | 0.83 | NAAA (0.38) | NAAAGAAREN | |
| SCHEMBL19084175 | 0.83 | GAA (0.43) | NAAAGAAF2F10PRSS1 | |
| SCHEMBL17898718 | 0.82 | NAAA (0.36) | NAAAGAAREN | |
| SCHEMBL17898719 | 0.81 | REN (0.37) | NAAAREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |