Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17903383 | 0.94 | KMT2A (0.37) | KMT2AL3MBTL1CTSLCTSSCTSK | |
| SCHEMBL16605399 | 0.90 | KMT2A (0.41) | KMT2AL3MBTL1CTSKSCN9ANAAA | |
| SCHEMBL17426989 | 0.88 | KMT2A (0.44) | KMT2AL3MBTL1NAAAGAAKDM1A | |
| SCHEMBL19628393 | 0.87 | KMT2A (0.36) | KMT2AL3MBTL1SCN9ANAAA | |
| SCHEMBL17898712 | 0.86 | KDM1A (0.36) | KMT2AL3MBTL1CTSLCTSSCTSK | |
| SCHEMBL15370898 | 0.85 | NAAA (0.37) | KMT2AL3MBTL1NAAAGAA | |
| SCHEMBL16603743 | 0.85 | GAA (0.36) | NAAAGAA | |
| SCHEMBL17898714 | 0.84 | KDM1A (0.36) | KMT2AL3MBTL1CTSLCTSSCTSK | |
| SCHEMBL17898912 | 0.84 | GAA (0.40) | CTSLCTSSCTSKGAA | |
| SCHEMBL16603880 | 0.84 | SCN9A (0.36) | CTSSCTSKSCN9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |