Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | CTSV | O60911 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19628405 | 0.93 | GAA (0.42) | GAACTSDBACE1CTSVCTSL | |
| SCHEMBL17898714 | 0.89 | KDM1A (0.36) | GAACTSDCTSLCTSSCTSK | |
| SCHEMBL17898712 | 0.89 | KDM1A (0.36) | GAACTSDCTSLCTSSCTSK | |
| SCHEMBL19091112 | 0.87 | GAA (0.42) | GAACTSDBACE1CTSVCTSL | |
| SCHEMBL17898809 | 0.85 | GAA (0.39) | GAACTSDBACE1 | |
| SCHEMBL17898754 | 0.84 | KMT2A (0.38) | GAACTSLCTSSCTSK | |
| SCHEMBL17898728 | 0.84 | GAA (0.39) | GAACTSD | |
| SCHEMBL19628422 | 0.83 | GAA (0.35) | GAACTSDNFKB1NFKB2RELA | |
| SCHEMBL19628423 | 0.80 | GAA (0.43) | GAACTSDBACE1NFKB1NFKB2 | |
| SCHEMBL17426991 | 0.80 | GAA (0.43) | GAACTSDBACE1CTSKNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |