Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 10/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 2/20 | 0.31 |
| ▸ | MET | P08581 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898773 | 0.96 | HPGDS (0.33) | HPGDSRIPK1PTK2PTK2BGRM5 | |
| SCHEMBL19628458 | 0.94 | RIPK1 (0.33) | RIPK1PTK2PTK2BGRM5MEN1 | |
| SCHEMBL15366680 | 0.93 | HPGDS (0.31) | HPGDSRIPK1 | |
| SCHEMBL17899026 | 0.93 | HPGDS (0.31) | HPGDSRIPK1MEN1CYP1A2KMT2A | |
| SCHEMBL17898780 | 0.92 | HPGDS (0.30) | HPGDS | |
| SCHEMBL17899024 | 0.92 | HPGDS (0.30) | HPGDS | |
| SCHEMBL17899027 | 0.91 | RIPK1 (0.30) | HPGDSRIPK1 | |
| SCHEMBL17898891 | 0.91 | RIPK1 (0.30) | HPGDSRIPK1 | |
| SCHEMBL19091125 | 0.90 | GRM4 (0.34) | RIPK1PTK2PTK2BGRM5IGF1R | |
| SCHEMBL19066904 | 0.90 | GRM4 (0.34) | RIPK1PTK2PTK2BGRM5IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |