Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 6/20 | 0.39 |
| ▸ | BACE1 | P56817 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15366231 | 0.92 | CTSD (0.37) | CTSDBACE1GAANAAA | |
| SCHEMBL15366233 | 0.92 | CTSD (0.37) | CTSDBACE1GAANAAA | |
| SCHEMBL15366236 | 0.92 | CTSD (0.37) | CTSDBACE1GAANAAA | |
| SCHEMBL17898906 | 0.90 | CTSD (0.37) | CTSDBACE1GAANAAA | |
| SCHEMBL19091499 | 0.88 | GAA (0.41) | CTSDBACE1GAANAAA | |
| SCHEMBL17898648 | 0.85 | BCHE (0.37) | CTSDBACE1GAANAAA | |
| SCHEMBL17898649 | 0.85 | GAA (0.39) | CTSDBACE1GAANAAA | |
| SCHEMBL19091089 | 0.84 | GAA (0.43) | CTSDBACE1GAANAAA | |
| SCHEMBL17898840 | 0.83 | NAAA (0.40) | NAAA | |
| SCHEMBL19633453 | 0.82 | GAA (0.41) | CTSDBACE1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |