Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089230 | 0.95 | PDE4D (0.34) | PDE4D | |
| SCHEMBL19084192 | 0.91 | NPC1 (0.32) | — | |
| SCHEMBL17898767 | 0.89 | PDE4D (0.33) | PDE4D | |
| SCHEMBL19089231 | 0.88 | PDE4D (0.34) | PDE4D | |
| SCHEMBL17428146 | 0.87 | F2R (0.31) | — | |
| SCHEMBL19089224 | 0.87 | PDE4D (0.33) | PDE4D | |
| SCHEMBL16603812 | 0.86 | — | — | |
| SCHEMBL19089232 | 0.86 | RIPK1 (0.32) | PDE4D | |
| SCHEMBL19091554 | 0.85 | ESR1 (0.32) | PDE4D | |
| SCHEMBL19091552 | 0.85 | ESR1 (0.32) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |