Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089231 | 0.91 | PDE4D (0.34) | PDE4D | |
| SCHEMBL19089417 | 0.91 | ROCK1 (0.32) | RIPK1ROCK1ROCK2PDE10A | |
| SCHEMBL19089230 | 0.90 | PDE4D (0.34) | RIPK1PDE4D | |
| SCHEMBL19088922 | 0.90 | RIPK1 (0.35) | RIPK1ROCK1ROCK2PDE4APDE4B | |
| SCHEMBL17898781 | 0.88 | ROCK1 (0.32) | RIPK1ROCK1 | |
| SCHEMBL19088927 | 0.88 | TAS1R3 (0.33) | RIPK1ROCK1ROCK2PDE4APDE4B | |
| SCHEMBL17899005 | 0.86 | PDE4D (0.33) | PDE4D | |
| SCHEMBL19091646 | 0.85 | PDE4A (0.31) | RIPK1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17427151 | 0.85 | RIPK1 (0.35) | RIPK1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19091645 | 0.85 | ADORA2A (0.31) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116949-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | WO | disclosed |