Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 2/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898874 | 0.88 | HPGDS (0.32) | HPGDSKMT2A | |
| SCHEMBL19628447 | 0.88 | MERTK (0.36) | KMT2AMEN1CYP1A2 | |
| SCHEMBL17898752 | 0.87 | LRRK2 (0.35) | — | |
| SCHEMBL15373806 | 0.86 | MERTK (0.38) | CYP1A2 | |
| SCHEMBL15366475 | 0.86 | MERTK (0.38) | CYP1A2 | |
| SCHEMBL15366755 | 0.86 | MERTK (0.38) | CYP1A2 | |
| SCHEMBL15373755 | 0.86 | MERTK (0.38) | CYP1A2 | |
| SCHEMBL15373805 | 0.86 | MERTK (0.38) | CYP1A2 | |
| SCHEMBL19099485 | 0.86 | NPC1 (0.36) | CSF1RKDM4EASPHKDM8 | |
| SCHEMBL19066608 | 0.86 | NPC1 (0.36) | CSF1RKDM4EASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |