Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364406 | 1.00 | SCN9A (0.36) | SCN9AKDM4DCACNA1GGAA | |
| SCHEMBL15363774 | 0.92 | NAAA (0.38) | — | |
| SCHEMBL15363775 | 0.92 | NAAA (0.38) | — | |
| SCHEMBL15363927 | 0.85 | GAA (0.37) | GAA | |
| SCHEMBL15363925 | 0.85 | GAA (0.37) | GAA | |
| SCHEMBL15363919 | 0.85 | GAA (0.38) | GAA | |
| SCHEMBL15363921 | 0.85 | GAA (0.38) | GAA | |
| SCHEMBL17899061 | 0.85 | SCN9A (0.36) | SCN9AKDM4DGAA | |
| SCHEMBL15371967 | 0.84 | GAA (0.36) | SCN9AGAA | |
| SCHEMBL15363721 | 0.84 | GAA (0.38) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150289508-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-10-15 | — | — | US | disclosed |
| US-9131690-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2015-09-15 | — | — | US | disclosed |
| US-20130296371-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2013-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296371-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, FKBP14 | SCN9A 1809/4885KDM4D 3002/4885CACNA1G 1416/4885 |
| US-20150289508-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, FKBP14 | SCN9A 1809/4885KDM4D 3002/4885CACNA1G 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.