Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1915754 | 0.94 | MAPT (0.58) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL2396558 | 0.90 | ALDH1A1 (0.60) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL1916767 | 0.88 | MAPT (0.69) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL1914731 | 0.85 | ALDH1A1 (0.62) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL1915954 | 0.85 | MAPT (0.66) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL1915349 | 0.84 | ALDH1A1 (0.60) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2398140 | 0.83 | ALDH1A1 (0.76) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL1915536 | 0.83 | ALDH1A1 (0.60) | MAPTALDH1A1HTTPOLBTDP1 | |
| SCHEMBL2417767 | 0.82 | MAPT (0.60) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL17899118 | 0.82 | ALDH1A1 (0.74) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266527-B2 | T-box riboswitch-binding anti-bacterial compounds | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF ALBANY (US) | 2019-04-23 | — | — | US | disclosed |
| US-20160194317-A1 | T-BOX RIBOSWITCH-BINDING ANTI-BACTERIAL COMPOUNDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266527-B2 | T-box riboswitch-binding anti-bacterial compounds | TARBP1, AARS1, NSUN3 | MAPT 4117/4885CYP1A2 4492/4885CYP2C9 4248/4885 |
| US-20160194317-A1 | T-BOX RIBOSWITCH-BINDING ANTI-BACTERIAL COMPOUNDS | TARBP1, AARS1, NSUN3 | MAPT 4117/4885CYP1A2 4492/4885CYP2C9 4248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.