Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | KCNJ11 | Q14654 | 14/20 | 0.50 |
| ▸ | ABCC9 | O60706 | 7/20 | 0.50 |
| ▸ | ABCC8 | Q09428 | 7/20 | 0.50 |
| ▸ | KCNJ8 | Q15842 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL589730 | 0.82 | HPGD (0.67) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14703304 | 0.80 | KCNJ11 (0.46) | HPGDHSD17B10KCNJ11ABCC9ABCC8 | |
| SCHEMBL22473836 | 0.80 | HSD17B10 (0.59) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7304753 | 0.80 | HSD17B10 (0.59) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2220947 | 0.80 | HSD17B10 (0.59) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5596451 | 0.77 | HSD17B10 (0.56) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL23861465 | 0.76 | CYP1A2 (0.51) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8384856 | 0.75 | HSD17B10 (0.59) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11954780 | 0.75 | CYP1A2 (0.58) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL23861600 | 0.75 | PTPN22 (0.53) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9995719-B2 | Methods and devices for selective deposition of materials including mechanical abrasion | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-06-12 | — | — | US | disclosed |
| US-9459222-B2 | Methods for deposition of materials including mechanical abrasion | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-10-04 | — | — | US | disclosed |
| US-20160195504-A1 | METHODS AND DEVICES FOR DEPOSITION OF MATERIALS ON PATTERNED SUBSTRATES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-07-07 | — | — | US | disclosed |