SCHEMBL589730

SCHEMBL589730

Oc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.67
HSD17B10 Q99714 2/20 0.67
KDM4E B2RXH2 1/20 0.67
MEN1 O00255 1/20 0.67
ALDH1A1 P00352 1/20 0.67
GLA P06280 1/20 0.67
POLB P06746 1/20 0.67
GAA P10253 1/20 0.67
MAPT P10636 1/20 0.67
KMT2A Q03164 1/20 0.67
ATM Q13315 1/20 0.67
CYP1A2 P05177 1/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
HIF1A Q16665 1/20 0.59
KCNJ11 Q14654 17/20 0.56
ABCC9 O60706 9/20 0.56
ABCC8 Q09428 9/20 0.56
KCNJ8 Q15842 9/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3885735 0.82 KDM4E (0.68) HPGDHSD17B10KDM4EMEN1ALDH1A1
SCHEMBL7304753 0.82 HSD17B10 (0.59) HPGDHSD17B10KDM4EMEN1ALDH1A1
SCHEMBL17899124 0.82 HPGD (0.56) HPGDHSD17B10KDM4EMEN1ALDH1A1
SCHEMBL14593291 0.82 KDM4E (0.66) HPGDHSD17B10KDM4EMEN1ALDH1A1
SCHEMBL7258624 0.80 KDM4E (1.00) HPGDHSD17B10KDM4EMEN1ALDH1A1
SCHEMBL5566472 0.80 KDM4E (1.00) HPGDHSD17B10KDM4EMEN1ALDH1A1
SCHEMBL7112409 0.75 KDM4E (0.62) HPGDHSD17B10KDM4EMEN1ALDH1A1
SCHEMBL22473836 0.75 HSD17B10 (0.59) HPGDHSD17B10MEN1ALDH1A1KMT2A
SCHEMBL2220947 0.75 HSD17B10 (0.59) HPGDHSD17B10MEN1ALDH1A1KMT2A
SCHEMBL13856943 0.74 HSD17B10 (1.00) HPGDHSD17B10KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12163968-B2 Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers BIO-RAD LABORATORIES, INC. (US) 2024-12-10 US claimed
US-12277464-B2 System for detecting a stimulus including a radio frequency device responsive to an analyte and a portable reader MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-04-15 US disclosed
US-20250028923-A1 Chemical and Physical Sensing with a Reader and RFID Tags MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-01-23 US disclosed
US-12163968-B2 Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers BIO-RAD LABORATORIES, INC. (US) 2024-12-10 US disclosed
EP-4394738-A2 CHEMICAL AND PHYSICAL SENSING WITH A READER AND RFID TAGS Massachusetts Institute of Technology (US) 2024-07-03 EP disclosed
EP-4365589-A2 CHEMIRESISTOR WITH IONIC LIQUID CARBON NANOTUBE COMPOSITE FOR WIRELESS CHEMICAL SENSING Massachusetts Institute of Technology (US) 2024-05-08 EP disclosed
EP-3063700-B1 CHEMICAL AND PHYSICAL SENSING WITH A READER AND RFID TAGS MASSACHUSETTS INST TECHNOLOGY (US) 2024-04-17 EP disclosed
EP-3507595-B1 CHEMIRESISTOR WITH CARBON NANOTUBE COMPOSITE FOR WIRELESS CHEMICAL SENSING MASSACHUSETTS INST TECHNOLOGY (US) 2024-01-24 EP disclosed
US-11861437-B2 Chemical and physical sensing with a reader and RFID tags MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-01-02 US disclosed
EP-4208021-A1 PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS Bio-Rad Laboratories, Inc. (US) 2023-07-12 EP disclosed
US-20160195504-A1 METHODS AND DEVICES FOR DEPOSITION OF MATERIALS ON PATTERNED SUBSTRATES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-07-07 US disclosed
US-20150116093-A1 CHEMICAL AND PHYSICAL SENSING WITH A READER AND RFID TAGS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2015-04-30 US disclosed
EP-2376908-B1 SIMULATION OF NORMAL FRESH BLOOD PLATELETS BIO RAD LABORATORIES (US) 2014-12-31 EP disclosed
US-20130330231-A1 METHODS FOR DEPOSITION OF MATERIALS INCLUDING MECHANICAL ABRASION MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-12-12 US disclosed
WO-2013180801-A1 METHODS FOR DEPOSITION OF MATERIALS INCLUDING MECHANICAL ABRASION MASSACHUSSETTS INSTITUTE OF TECHNOLOGY (US) 2013-12-05 WO disclosed
US-8114580-B2 Simulation of normal fresh blood platelets for reference control BIO-RAD LABORATORIES, INC. (US) 2012-02-14 US disclosed
US-20100178647-A1 SIMULATION OF NORMAL FRESH BLOOD PLATELETS BIO-RAD LABORATORIES, INC. (US) 2010-07-15 US disclosed
US-4283537-A Thiazine-1,1-dioxide and isothiazole-1,1-dioxide derivatives and process for preparation POLAROID CORPORATION (US) 1981-08-11 US disclosed
US-4056539-A OPTICAL FILTERS POLAROID CORPORATION (US) 1977-11-01 US disclosed
US-4010168-A Naphthalide indicator dyes POLAROID CORPORATION (US) 1977-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100178647-A1 SIMULATION OF NORMAL FRESH BLOOD PLATELETS MPL, THPO, PFKP HPGD 1205/4885HSD17B10 4436/4885KDM4E 3264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.