SCHEMBL17899173

SCHEMBL17899173

c1ccc(-c2cccc(-c3cc(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)nc(-c4ccccc4)n3)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.48
MEN1 O00255 7/20 0.48
MAPT P10636 7/20 0.48
HPGD P15428 7/20 0.48
ALDH1A1 P00352 6/20 0.48
KDM4E B2RXH2 5/20 0.48
LMNA P02545 2/20 0.48
GLA P06280 1/20 0.48
NTSR1 P30989 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ATM Q13315 1/20 0.46
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
MAOB P27338 3/20 0.40
MAOA P21397 2/20 0.40
HDAC4 P56524 1/20 0.39
NPSR1 Q6W5P4 2/20 0.39
RXFP1 Q9HBX9 1/20 0.39
CYP2C19 P33261 1/20 0.39
PTK2B Q14289 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8400278 1.00 KMT2A (0.48) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL22763700 1.00 KMT2A (0.48) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL74747 1.00 KMT2A (0.48) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL9881150 1.00 KMT2A (0.48) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL8400329 1.00 KMT2A (0.48) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL19276014 1.00 KMT2A (0.48) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL14425790 1.00 KMT2A (0.48) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL14426186 0.99 KMT2A (0.47) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL8400326 0.99 KMT2A (0.47) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL14425767 0.99 KMT2A (0.47) KMT2AMEN1MAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
WO-2019078461-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2019-04-25 WO disclosed
US-20170244044-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-24 US disclosed
US-20170244044-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-24 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 KMT2A 3009/4885MEN1 975/4885MAPT 1926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.