Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | MET | P08581 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17897665 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL13531666 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL6153438 | 0.81 | MAPK1 (0.42) | SMN1; SMN2LMNAMETPOLBHTT | |
| SCHEMBL17899463 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL11098893 | 0.79 | SMN1; SMN2 (0.73) | SMN1; SMN2KDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL24235951 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL11113253 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL10510362 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL16322670 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL11097790 | 0.74 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4ECYP1A2GRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160193347-A1 | MULTI-TARGETED UBENIMEX PRODRUG DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | WEIFANG BOCHUANG INTERNATIONAL ACADEMY OF BIOTECHNOLOGY AND MEDICINE (CN) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160193347-A1 | MULTI-TARGETED UBENIMEX PRODRUG DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | ANPEP, DNPEP, ENPEP | SMN1; SMN2 4469/4885KDM4E 1194/4885CYP1A2 2340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.