Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 7/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.42 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 11/20 | 0.35 |
| ▸ | HTR2A | P28223 | 11/20 | 0.35 |
| ▸ | DRD3 | P35462 | 11/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17894548 | 1.00 | SLC9A1 (0.52) | SLC9A1MTNR1BSLC9A5SLC9A2DRD2 | |
| SCHEMBL19699402 | 1.00 | SLC9A1 (0.52) | SLC9A1MTNR1BSLC9A5SLC9A2DRD2 | |
| SCHEMBL17894547 | 1.00 | SLC9A1 (0.52) | SLC9A1MTNR1BSLC9A5SLC9A2DRD2 | |
| SCHEMBL6679812 | 0.82 | KDM4E (0.38) | SLC9A1DRD2 | |
| SCHEMBL6679801 | 0.82 | KDM4E (0.38) | SLC9A1DRD2 | |
| SCHEMBL6679807 | 0.82 | KDM4E (0.38) | SLC9A1DRD2 | |
| SCHEMBL6682308 | 0.81 | SLC9A1 (0.52) | SLC9A1MTNR1BSLC9A5SLC9A2DRD2 | |
| SCHEMBL6678123 | 0.81 | SLC9A1 (0.52) | SLC9A1MTNR1BSLC9A5SLC9A2DRD2 | |
| SCHEMBL19699401 | 0.81 | SLC9A1 (0.52) | SLC9A1MTNR1BSLC9A5SLC9A2DRD2 | |
| SCHEMBL19699403 | 0.75 | MTNR1B (0.64) | SLC9A1MTNR1BSLC9A5SLC9A2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109359-A1 | CYCLOPROPYL DIHYDROBENZOFURAN MODULATORS OF MELATONIN RECEPTORS | AUSPEX PHARMACEUTICALS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |