Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17227653 | 0.88 | L3MBTL1 (0.37) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL20023682 | 0.87 | PDK2 (0.36) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL24255866 | 0.87 | PDK2 (0.38) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL24255845 | 0.87 | PDK2 (0.36) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL17893795 | 0.87 | MEN1 (0.41) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL17899961 | 0.86 | L3MBTL1 (0.37) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL17899967 | 0.86 | MAPT (0.41) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL17899968 | 0.85 | MEN1 (0.38) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL2606100 | 0.85 | PDE5A (0.30) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL15866660 | 0.85 | MEN1 (0.40) | MEN1KMT2AKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329483-B2 | Fluorene derivatives as light emitting elements for electroluminescent devices | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-06-25 | — | — | US | disclosed |
| US-20180002597-A1 | Fluorene Derivatives as Light Emitting Elements for Electroluminescent Devices | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2018-01-04 | — | — | US | disclosed |
| WO-2016109274-A1 | FLUORENE DERIVATIVES AS LIGHT EMITTING ELEMENTS FOR ELECTROLUMINESCENT DEVICES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329483-B2 | Fluorene derivatives as light emitting elements for electroluminescent devices | LEF1, AFF2, CELF2 | MEN1 1722/4885KMT2A 664/4885KDM4E 3225/4885 |
| US-20180002597-A1 | Fluorene Derivatives as Light Emitting Elements for Electroluminescent Devices | LEF1, AFF2, CELF2 | MEN1 1722/4885KMT2A 664/4885KDM4E 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.