Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20627013 | 1.00 | TDP1 (0.36) | TDP1MAPTATMMEN1KMT2A | |
| SCHEMBL17901543 | 1.00 | TDP1 (0.36) | TDP1MAPTATMMEN1KMT2A | |
| SCHEMBL17901517 | 0.92 | GAA (0.37) | TDP1MAPTATMMEN1KMT2A | |
| SCHEMBL17901448 | 0.92 | CASR (0.36) | TDP1MAPTGAARAB9A | |
| SCHEMBL17901446 | 0.92 | TDP1 (0.35) | TDP1MAPTATMMEN1KMT2A | |
| SCHEMBL17901420 | 0.92 | MAPT (0.37) | TDP1MAPTMEN1KMT2AGAA | |
| SCHEMBL17901455 | 0.91 | ATM (0.40) | TDP1MAPTATMPOLBALDH1A1 | |
| SCHEMBL17901476 | 0.91 | MCHR1 (0.35) | ATMCTSA | |
| SCHEMBL17901469 | 0.90 | TDP1 (0.40) | TDP1MAPTATMMEN1KMT2A | |
| SCHEMBL17901452 | 0.90 | TAS1R3 (0.39) | TDP1MAPTATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240408-B1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-04-08 | — | — | EP | disclosed |
| US-20190359557-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2019-11-28 | — | — | US | disclosed |
| US-10252989-B2 | Picolinamides with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-04-09 | — | — | US | disclosed |
| US-10173971-B2 | Picolinamides with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180037541-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2018-02-08 | — | — | US | disclosed |
| WO-2016109300-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109301-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037541-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | CYP51A1, CYP1A2, FKBP14 | TDP1 2339/4885MAPT 2315/4885ATM 4794/4885 |
| US-20190359557-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | CYP51A1, CYP1A2, FKBP14 | TDP1 2339/4885MAPT 2315/4885ATM 4794/4885 |
| US-10173971-B2 | Picolinamides with fungicidal activity | CYP51A1, CYP1A2, FKBP14 | TDP1 2339/4885MAPT 2315/4885ATM 4794/4885 |
| US-10252989-B2 | Picolinamides with fungicidal activity | CYP51A1, CYP1A2, FKBP14 | TDP1 2339/4885MAPT 2315/4885ATM 4794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.