Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17901515 | 1.00 | CTSK (0.46) | CTSK | |
| SCHEMBL17901514 | 0.87 | ATM (0.47) | CTSK | |
| SCHEMBL17901513 | 0.87 | ATM (0.47) | CTSK | |
| SCHEMBL17906532 | 0.86 | CTSK (0.43) | CTSK | |
| SCHEMBL17901087 | 0.83 | CTSK (0.43) | CTSK | |
| SCHEMBL17901082 | 0.83 | CTSK (0.43) | CTSK | |
| SCHEMBL17901123 | 0.83 | CTSK (0.43) | CTSK | |
| SCHEMBL17901143 | 0.83 | CTSK (0.43) | CTSK | |
| SCHEMBL17901043 | 0.83 | CTSK (0.48) | CTSK | |
| SCHEMBL17901045 | 0.83 | CTSK (0.48) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240408-B1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-04-08 | — | — | EP | disclosed |
| US-10252989-B2 | Picolinamides with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-04-09 | — | — | US | disclosed |
| US-10173971-B2 | Picolinamides with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-01-08 | — | — | US | disclosed |
| WO-2016109300-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109301-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10173971-B2 | Picolinamides with fungicidal activity | CYP51A1, CYP1A2, FKBP14 | CTSK 2781/4885 |
| US-10252989-B2 | Picolinamides with fungicidal activity | CYP51A1, CYP1A2, FKBP14 | CTSK 2781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.