Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20628463 | 0.84 | POLB (0.35) | AGBL2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL17896023 | 0.84 | POLB (0.37) | AGBL2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL16389599 | 0.83 | POLB (0.34) | AGBL2POLB | |
| SCHEMBL20628411 | 0.82 | POLB (0.32) | ALDH1A1NPC1RAB9AMEN1STAT3 | |
| SCHEMBL17901855 | 0.81 | POLB (0.33) | AGBL2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL20634569 | 0.77 | FGFR1 (0.31) | — | |
| SCHEMBL18624694 | 0.76 | RAB9A (0.46) | ALDH1A1NPC1RAB9AMEN1STAT3 | |
| SCHEMBL17008988 | 0.75 | RAB9A (0.43) | ALDH1A1NPC1RAB9AMEN1STAT3 | |
| SCHEMBL18624690 | 0.74 | SMN1; SMN2 (0.34) | AGBL2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL17008990 | 0.73 | SMN1; SMN2 (0.33) | AGBL2ALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016107831-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2016-07-07 | — | — | WO | disclosed |