Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17901849 | 0.87 | POLB (0.32) | POLBAGBL2 | |
| SCHEMBL17901811 | 0.86 | POLB (0.36) | POLB | |
| SCHEMBL17895956 | 0.84 | POLB (0.35) | POLBAGBL2ALDH1A1PKM | |
| SCHEMBL20847510 | 0.83 | POLB (0.32) | POLB | |
| SCHEMBL17901848 | 0.81 | AGBL2 (0.35) | POLBAGBL2KDM4EALDH1A1NPC1 | |
| SCHEMBL19755914 | 0.78 | — | — | |
| SCHEMBL17901875 | 0.77 | POLB (0.39) | POLBAGBL2KDM4EALDH1A1 | |
| SCHEMBL19755915 | 0.77 | POLB (0.37) | POLBAGBL2KDM4EALDH1A1 | |
| SCHEMBL17901879 | 0.76 | — | — | |
| SCHEMBL20847336 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016107831-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2016-07-07 | — | — | WO | disclosed |