SCHEMBL17902767

SCHEMBL17902767

NC(CCCCB(O)O)(C(=O)O)C1CCN(S(N)(=O)=O)CC1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 20/20 0.67
ARG2 P78540 19/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17896131 0.99 ARG1 (0.66) ARG1ARG2
SCHEMBL17902763 0.87 ARG1 (0.64) ARG1ARG2
Hydrochloric Acid SCHEMBL17896089 0.86 ARG1 (0.63) ARG1ARG2
SCHEMBL20683459 0.82 ARG1 (0.78) ARG1ARG2
SCHEMBL20683438 0.82 ARG1 (0.78) ARG1ARG2
SCHEMBL20683486 0.82 ARG1 (0.78) ARG1ARG2
SCHEMBL895696 0.82 ARG1 (0.65) ARG1ARG2
SCHEMBL21181006 0.82 ARG1 (0.65) ARG1ARG2
Hydrochloric Acid SCHEMBL895815 0.81 ARG1 (0.64) ARG1ARG2
SCHEMBL894860 0.81 ARG1 (0.64) ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3240777-B1 ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS ONCOARENDI THERAPEUTICS SA (PL) 2019-07-24 EP disclosed
EP-3240777-B1 ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS ONCOARENDI THERAPEUTICS SA (PL) 2019-07-24 EP disclosed
US-10329310-B2 Arginase inhibitors and their therapeutic applications ONCO ARENDI THERAPEUTICS S.A. (PL) 2019-06-25 US disclosed
US-20180009830-A1 ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS ONCO ARENDI THERAPEUTICS S.A. (PL) 2018-01-11 US disclosed
WO-2016108707-A1 ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS OncoArendi Therapeutics Sp. z o.o. (PL) 2016-07-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180009830-A1 ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS ARG1, ARG2, PRMT1 ARG1 1/4885ARG2 2/4885
US-10329310-B2 Arginase inhibitors and their therapeutic applications ARG1, ARG2, PRMT1 ARG1 1/4885ARG2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.