SCHEMBL17902815

SCHEMBL17902815

CCc1nnc(NC)o1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12343974 0.79 TP53 (0.46)
SCHEMBL8388694 0.76
SCHEMBL22905215 0.76 ALOX5 (0.33)
SCHEMBL3765666 0.74 KMT2A (0.48)
SCHEMBL17790247 0.71 ROCK2 (0.30)
SCHEMBL15025234 0.71 SMN1; SMN2 (0.30)
SCHEMBL12701583 0.70 HRH3 (0.55)
SCHEMBL21085353 0.70 ALOX5 (0.31)
SCHEMBL762438 0.67
SCHEMBL18901152 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024026500-A2 INHIBITORS OF PDE11A4 AND METHODS OF USING SAME UNIVERSITY OF MARYLAND, BALTIMORE (US) 2024-02-01 WO disclosed
WO-2020249785-A1 SUBSTITUTED HETEROAROMATIC PYRAZOLO-PYRIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2020-12-17 WO disclosed
WO-2020150417-A2 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY IFM DUE, INC. (US) 2020-07-23 WO disclosed
WO-2017193030-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES (US) 2017-11-09 WO disclosed
US-20160194284-A1 ALLOSTERIC MODULATORS OF THE CANNABINOID 1 RECEPTOR NORTHEASTERN UNIVERSITY (US) 2016-07-07 US disclosed