SCHEMBL1790336

SCHEMBL1790336

CCC(C)CCOC(=O)c1cccc(C(=O)OCCC(C)CC)c1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
TSHR P16473 1/20 0.47
MAPT P10636 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MEN1 O00255 1/20 0.45
PKM P14618 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
KDM4E B2RXH2 1/20 0.43
GAA P10253 1/20 0.43
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27778192 0.94 MAPT (0.52) LMNATSHRMAPTSMN1; SMN2KMT2A
SCHEMBL14399225 0.90 CHRM2 (0.49) LMNATSHRMAPTALDH1A1GAA
SCHEMBL9627498 0.89 LMNA (0.64) LMNATSHRMAPTSMN1; SMN2KMT2A
SCHEMBL25891800 0.89 LMNA (0.64) LMNATSHRMAPTSMN1; SMN2KMT2A
SCHEMBL23855447 0.86 MAPT (0.60) LMNATSHRMAPTSMN1; SMN2ALDH1A1
SCHEMBL3358303 0.86 SLC7A5 (0.47) LMNATSHRSMN1; SMN2KMT2AALDH1A1
SCHEMBL5371533 0.85 KMT2A (0.58) LMNATSHRMAPTSMN1; SMN2KMT2A
SCHEMBL5382671 0.83 MAPT (0.66) TSHRMAPTALDH1A1MAPK1
SCHEMBL21368451 0.83 CA12 (0.62) TSHRMAPTALDH1A1PKMTDP1
SCHEMBL28895855 0.83 EGFR (0.47) LMNATSHRSMN1; SMN2KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8932194-B2 Electrically conductive roller BRIDGESTONE CORPORATION (JP) 2015-01-13 US disclosed
EP-2151719-B1 ELECTRICALLY CONDUCTIVE ROLLER BRIDGESTONE CORP (JP) 2013-07-24 EP disclosed
US-20110124478-A1 ELECTRICALLY CONDUCTIVE ROLLER BRIDGESTONE CORPORATION (JP) 2011-05-26 US disclosed
EP-2151719-A1 ELECTRICALLY CONDUCTIVE ROLLER Bridgestone Corporation (JP) 2010-02-10 EP disclosed