Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13816042 | 0.89 | MAPT (0.57) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL442774 | 0.88 | MAPT (0.78) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL6444519 | 0.87 | MAPT (0.50) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL29665078 | 0.86 | ALDH1A1 (0.65) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL30513501 | 0.86 | ALDH1A1 (0.65) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL21143378 | 0.86 | ADRB2 (0.49) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL5368475 | 0.85 | MAPT (0.86) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL5374687 | 0.84 | ALDH1A1 (0.55) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL109308 | 0.84 | ALDH1A1 (0.61) | ADRB2ADRB1ADRB3ALDH1A1TSHR | |
| SCHEMBL1790336 | 0.83 | LMNA (0.49) | MAPTALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194396-B1 | SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS | BASF AG (DE) | 2005-11-09 | — | — | EP | claimed |
| US-7208545-B1 | Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-24 | — | — | US | disclosed |