Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 10/20 | 0.52 |
| ▸ | EGFR | P00533 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23373820 | 0.83 | KMT2A (0.46) | ALDH1A1HPGDSMN1; SMN2DNM1EGFR | |
| SCHEMBL10253234 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HPGDSMN1; SMN2DNM1EGFR | |
| SCHEMBL24273040 | 0.82 | KMT2A (0.45) | ALDH1A1HPGDSMN1; SMN2DNM1EGFR | |
| SCHEMBL16301931 | 0.81 | EGFR (0.50) | ALDH1A1HPGDSMN1; SMN2DNM1EGFR | |
| SCHEMBL23373825 | 0.80 | KMT2A (0.43) | ALDH1A1HPGDSMN1; SMN2DNM1EGFR | |
| SCHEMBL16353428 | 0.80 | MEN1 (0.53) | ALDH1A1HPGDSMN1; SMN2DNM1EGFR | |
| SCHEMBL22295766 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HPGDSMN1; SMN2DNM1EGFR | |
| SCHEMBL23373764 | 0.78 | KMT2A (0.42) | ALDH1A1HPGDSMN1; SMN2DNM1EGFR | |
| SCHEMBL17903534 | 0.78 | ALDH1A1 (0.45) | ALDH1A1DNM1EGFRLMNAPOLB | |
| SCHEMBL14540647 | 0.77 | SLC16A3 (0.47) | ALDH1A1HPGDEGFRKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160195519-A1 | FLUORESCENT MOLECULAR ROTORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160195519-A1 | FLUORESCENT MOLECULAR ROTORS | DYNC1LI2, DNAH12, DYNLL2 | ALDH1A1 3536/4885HPGD 4250/4885SMN1; SMN2 4781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.