SCHEMBL1790405

SCHEMBL1790405

CC(C)(C)c1cc(F)cc(COC(=O)O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP12 P39900 1/20 0.38
FFAR4 Q5NUL3 1/20 0.37
RXRA P19793 3/20 0.36
RXRB P28702 3/20 0.36
RXRG P48443 2/20 0.36
HCAR2 Q8TDS4 1/20 0.36
ELANE P08246 1/20 0.36
CD69 Q07108 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.35
IDO1 P14902 2/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1790404 0.89 MEN1 (0.47) MEN1KMT2ASMN1; SMN2L3MBTL1MMP1
SCHEMBL1789188 0.88 GABRA1 (0.45) MEN1KMT2ASMN1; SMN2L3MBTL1RXRA
SCHEMBL1789980 0.84 RXRA (0.36) MEN1KMT2ASMN1; SMN2L3MBTL1FFAR4
SCHEMBL1791164 0.82 IDO1 (0.50) MMP1MMP2MMP9MMP12HCAR2
SCHEMBL1790738 0.79 MAPT (0.40) MEN1KMT2ASMN1; SMN2L3MBTL1RXRA
SCHEMBL1789981 0.76 SMN1; SMN2 (0.36) MEN1KMT2ASMN1; SMN2L3MBTL1RXRA
SCHEMBL1789187 0.75 GABRA1 (0.46) MEN1KMT2ASMN1; SMN2L3MBTL1RXRA
SCHEMBL1788403 0.75 MRGPRX4 (0.50) MMP1MMP12RXRARXRBMRGPRX4
SCHEMBL14255479 0.74 FFAR4 (0.44) MEN1KMT2AFFAR4RXRARXRB
SCHEMBL1788830 0.74 NR4A2 (0.57) MEN1KMT2ASMN1; SMN2L3MBTL1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2249426-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY MITSUBISHI CHEM CORP (JP) 2019-07-10 EP disclosed
US-9083058-B2 Nonaqueous electrolytic solution and nonaqueous-electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2015-07-14 US disclosed
US-8916298-B2 Nonaqueous electrolytic solution and nonaqueous-electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2014-12-23 US disclosed
US-8889302-B2 Nonaqueous electrolytic solution and nonaqueous-electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2014-11-18 US disclosed
US-8846254-B2 2014-09-30 US disclosed
US-20140134481-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2014-05-15 US disclosed
US-20120308883-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-12-06 US disclosed
US-20120219854-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
US-20110123871-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMCIAL (JP) 2011-05-26 US disclosed
EP-2249426-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY Mitsubishi Chemical Corporation (JP) 2010-11-10 EP disclosed