Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907316 | 0.81 | ENPP2 (0.35) | DGAT1 | |
| SCHEMBL17907286 | 0.69 | ENPP2 (0.36) | DGAT1 | |
| SCHEMBL12208091 | 0.69 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL16532114 | 0.68 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL16532005 | 0.65 | TP53 (0.37) | DGAT1 | |
| SCHEMBL17907389 | 0.65 | TP53 (0.37) | DGAT1 | |
| SCHEMBL18086606 | 0.64 | TP53 (0.39) | DGAT1 | |
| SCHEMBL12208122 | 0.64 | MRGPRX4 (0.39) | DGAT1 | |
| SCHEMBL16531968 | 0.64 | TP53 (0.36) | DGAT1 | |
| SCHEMBL16532016 | 0.64 | DGAT1 (0.35) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042907-A1 | DGAT1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF | Medshine Discovery Inc. (CN) | 2016-07-13 | — | — | EP | disclosed |