Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | PLG | P00747 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | GABRP | O00591 | 3/20 | 0.59 |
| ▸ | GABRD | O14764 | 3/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.59 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.59 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.59 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1878849 | 0.98 | LMNA (0.65) | CYP2D6NFKB1LMNABLMNPSR1 | |
| Adipic Acid SCHEMBL10715338 | 0.98 | LMNA (0.65) | CYP2D6NFKB1LMNABLMNPSR1 | |
| SCHEMBL2031879 | 0.92 | GABRP (0.70) | CYP2D6NFKB1LMNAALDH1A1GABRP | |
| SCHEMBL6519193 | 0.92 | GABRP (0.70) | CYP2D6NFKB1LMNAALDH1A1GABRP | |
| SCHEMBL1881592 | 0.90 | GABRP (0.67) | NFKB1LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL1882596 | 0.90 | GABRP (0.67) | NFKB1LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL1875146 | 0.90 | GABRP (0.67) | NFKB1LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL1882607 | 0.90 | GABRP (0.67) | NFKB1LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL244824 | 0.90 | GABRP (0.67) | NFKB1LMNAKMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7273348 | 0.90 | GABRP (0.67) | CYP2D6NFKB1LMNABLMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042924-A1 | POLYARYLENE SULFIDE RESIN AND MANUFACTURING METHOD THEREFOR, POLY(ARYLENE SULFONIUM SALT) AND MANUFACTURING METHOD THEREFOR, AND SULFOXIDE | DIC Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |